Optimizing Antimicrobial Therapy for Gram-Negative Infections

Thursday, December 6, 2012
2:30 PM – 4:00 PM

Planned in cooperation with the ASHP Section of Clinical Specialists and Scientists
Activity #: 204-000-12-207-L01P
Level of Content: Advanced
1.50 Contact Hours / Knowledge-based
Program Chair: Douglas Slain, PharmD, BCPS, FASHP

Learning Objectives:

• Identify clinical situations that would warrant double coverage of Gram-negative infections.
  
• Explain the role of double coverage and/or combination therapy in empiric therapy.
  
• Evaluate population pharmacokinetics/pharmacodynamics (PK/PD) modeling approaches used for dose optimization of antimicrobial therapy for Gram-negative infections.
  
• List advantages to applying PK/PD principles in the treatment of Gram-negative infections specifically related to extended infusion -lactams.
  
• Describe systematic approaches to implementing antimicrobial PK/PD dosing strategies in a clinical setting.